Herzog U, Putzke H P, Bienengräber V, Radke C
Klinik und Poliklinik für Zahn-, Mund- und Kieferheilkunde der Medizininschen Fakultät, Universität Rostock.
Dtsch Z Mund Kiefer Gesichtschir. 1991 Mar-Apr;15(2):90-3.
A case report is given on the rare course of an ameloblastic odontoma which originated from the right mandible in a girl at the age of 14. During the follow-up of 12 years there where 4 recurrences with a change in the histological findings. While ameloblastic epithelial complexes were found to be ever decreasing, there was, on the other hand, an increase in the mesenchymal component with foci of a marked proliferation of spindle cellular fibroblastic elements. Finally the condition progressed to an ameloblastic odontosarcoma appearing as a pleomorphic fibrosarcoma with a local metastasis. The clinical behaviour correlated with the histopathological findings.
本文报告了一例罕见的成釉细胞性牙瘤病例,该肿瘤起源于一名14岁女孩的右下颌骨。在12年的随访期间,肿瘤复发4次,组织学表现发生了变化。虽然发现成釉细胞上皮复合体不断减少,但另一方面,间充质成分增加,出现梭形细胞纤维母细胞成分显著增殖的病灶。最终病情进展为成釉细胞性牙肉瘤,表现为多形性纤维肉瘤并伴有局部转移。临床行为与组织病理学结果相关。