Carroll Nick J, Rathod Shailendra B, Derbins Erin, Mendez Sergio, Weitz David A, Petsev Dimiter N
Department of Chemical and Nuclear Engineering, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Langmuir. 2008 Feb 5;24(3):658-61. doi: 10.1021/la7032516. Epub 2008 Jan 3.
A novel method for the fabrication of monodisperse mesoporous silica particles is suggested. It is based on the formation of well-defined equally sized emulsion droplets using a microfluidic approach. The droplets contain the silica precursor/surfactant solution and are suspended in hexadecane as the continuous oil phase. The solvent is then expelled from the droplets, leading to concentration and micellization of the surfactant. At the same time, the silica solidifies around the surfactant structures, forming equally sized mesoporous particles. The procedure can be tuned to produce well-separated particles or alternatively particles that are linked together. The latter allows us to create 2D or 3D structures with hierarchical porosity.
提出了一种制备单分散介孔二氧化硅颗粒的新方法。该方法基于使用微流控方法形成尺寸明确且大小均匀的乳液滴。这些液滴包含二氧化硅前驱体/表面活性剂溶液，并悬浮在十六烷作为连续油相中。然后将溶剂从液滴中排出，导致表面活性剂浓缩并形成胶束。与此同时，二氧化硅在表面活性剂结构周围固化，形成尺寸均匀的介孔颗粒。该过程可以进行调整，以生产出分离良好的颗粒，或者生产出相互连接的颗粒。后者使我们能够创建具有分级孔隙率的二维或三维结构。
