瑞典一家胃肠病科病房丙型肝炎医院内传播的前瞻性研究。

Prospective study of nosocomial transmission of hepatitis C in a Swedish gastroenterology unit .

作者信息

Verbaan Hans, Molnegren Vilma, Pentmo Inez, Rubin Lena, Widell Anders

机构信息

Department of Medicine (H.V., L.R.),University of Lund, Malmö University Hospital, Malmö, Sweden.

出版信息

Infect Control Hosp Epidemiol. 2008 Jan;29(1):83-5. doi: 10.1086/524340.

DOI:10.1086/524340

PMID:18171195

Abstract

A prospective study of incident hepatitis C in 515 gastroenterology patients was conducted by follow-up sampling at 3-6 months after admission to the gastroenterology unit to test for antibodies to hepatitis C virus and for hepatitis C virus RNA. Universal precautions were implemented, and the use of multidose vials had been banned in this unit. Despite 5,964 exposure-days for several risk factors associated with nosocomial hepatitis C virus transmission, no incident case of hepatitis C occurred.

摘要

对515名胃肠病患者的丙型肝炎发病情况进行了一项前瞻性研究，在他们入住胃肠病科3至6个月后进行随访抽样，检测丙型肝炎病毒抗体和丙型肝炎病毒RNA。该科室实施了普遍预防措施，并已禁止使用多剂量瓶。尽管存在与医院内丙型肝炎病毒传播相关的几种危险因素，累计暴露天数达5964天，但未发生丙型肝炎发病病例。