Yoo Sonia H, Kymionis George D, Koreishi Aaleya, Ide Takeshi, Goldman David, Karp Carol L, O'Brien Terrence P, Culbertson William W, Alfonso Eduardo C
Department of Ophthalmology, Bascom Palmer Eye Institute-University of Miami School of Medicine, Miami, Florida, USA.
Ophthalmology. 2008 Aug;115(8):1303-7, 1307.e1. doi: 10.1016/j.ophtha.2007.10.037. Epub 2008 Jan 2.
To report the technique and small case series results of femtosecond laser-assisted sutureless anterior lamellar keratoplasty (FALK) for anterior corneal pathology.
Retrospective, noncomparative, interventional case series.
Twelve consecutive eyes from 12 patients with anterior corneal scarring.
Femtosecond laser-assisted sutureless anterior lamellar keratoplasty.
Measured parameters included femtosecond laser settings, technique, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and complications.
Mean follow-up was 12.7 months (range, 6-24). No intraoperative complications were found. Uncorrected visual acuity (VA) improved in 7 eyes (58.3%) compared with preoperative VA. The mean difference between preoperative and postoperative UCVAs was a gain of 2.5 lines (range, unchanged-7 lines). Best-corrected VA was unchanged or improved in all eyes compared with preoperative levels. The mean difference between preoperative and postoperative BCVAs was a gain of 3.8 lines (range, unchanged-8 lines). In 2 eyes, adjuvant surgical procedures were performed (one treated with phototherapeutic keratectomy and the other with photorefractive keratectomy). Six patients (50%) developed dry eye after FALK, which improved during the follow-up period. No graft rejection, infection, or epithelial ingrowth was found in this series of patients.
Femtosecond laser-assisted sutureless anterior lamellar keratoplasty could improve UCVA and BCVA in patients with anterior corneal pathology.
报告飞秒激光辅助无缝合前板层角膜移植术（FALK）治疗前部角膜病变的技术及小病例系列结果。
回顾性、非对照、干预性病例系列。
12例前部角膜瘢痕患者的12只连续眼。
飞秒激光辅助无缝合前板层角膜移植术。
测量参数包括飞秒激光设置、技术、未矫正视力（UCVA）、最佳矫正视力（BCVA）及并发症。
平均随访12.7个月（范围6 - 24个月）。未发现术中并发症。与术前视力相比，7只眼（58.3%）的未矫正视力（VA）有所改善。术前和术后UCVA的平均差值增加了2.5行（范围，无变化 - 7行）。与术前水平相比，所有眼的最佳矫正视力均未改变或有所改善。术前和术后BCVA的平均差值增加了3.8行（范围，无变化 - 8行）。2只眼接受了辅助手术（1只眼行光治疗性角膜切削术，另1只眼行准分子激光角膜原位磨镶术）。6例患者（50%）在FALK术后出现干眼，在随访期间有所改善。该系列患者未发现移植排斥、感染或上皮内生。
飞秒激光辅助无缝合前板层角膜移植术可改善前部角膜病变患者的UCVA和BCVA。
