Department of Ophthalmology, Army Hospital Research and Referral, New Delhi, India.
Department of Ophthalmology, Armed Forces Medical College, Pune, India; and.
Cornea. 2021 Jan;40(1):125-130. doi: 10.1097/ICO.0000000000002508.
To report a modified sutureless and glue-less technique, termed tuck in femtosecond laser assisted anterior lamellar keratoplasty (T-FALK), and to achieve a good graft-host junction apposition.
This is a prospective interventional case series of 15 eyes of 15 patients who underwent T-FALK. Depth of the anterior corneal scar was assessed using anterior segment optical coherence tomography (ASOCT). The donor and recipient lenticules were prepared using femtosecond laser. After removing the recipient anterior scarred lenticule, the transparent donor lenticule was positioned on the recipient bed and margins tucked in under the recipient cornea. A bandage contact lens was applied for 3 weeks. Postoperatively, topical antibiotic and steroid combination eye drops were given, and the assessment of healing of the graft-host junction was done using ASOCT.
A total of 15 patients (8 men and 7 women) underwent T-FALK. Six patients had superficial corneal opacities after healed microbial keratitis, 5 patients had spheroidal corneal degeneration, 3 patients had Salzman nodular degeneration, and 1 patient had vortex keratopathy. No intraoperative or postoperative complications were noted during T-FALK. All patients had good graft-host junction apposition postoperatively, as demonstrated by ASOCT.
Sutureless and glue-less T-FALK can be the best way ahead for management of superficial anterior corneal scars with good visual outcome.
报告一种改良的无缝线和无胶的技术,称为飞秒激光辅助前板层角膜移植术中的内卷(T-FALK),以实现良好的移植物-宿主交界处贴合。
这是一项前瞻性的 15 例 15 只眼的干预性病例系列研究,这些患者均接受了 T-FALK。使用眼前节光学相干断层扫描(ASOCT)评估前角膜瘢痕的深度。使用飞秒激光制备供体和受体角膜瓣。在去除受检者的前瘢痕角膜瓣后,将透明的供体角膜瓣置于受检者的床面,并将边缘内卷到受检者的角膜下。应用绷带接触镜 3 周。术后给予局部抗生素和皮质类固醇滴眼剂,并使用 ASOCT 评估移植物-宿主交界处的愈合情况。
共有 15 例患者(8 名男性和 7 名女性)接受了 T-FALK。6 例患者在微生物性角膜炎愈合后出现浅层角膜混浊,5 例患者出现球形角膜变性,3 例患者出现 Salzman 结节变性,1 例患者出现涡状角膜病变。在 T-FALK 过程中,未观察到术中或术后并发症。所有患者术后均通过 ASOCT 显示出良好的移植物-宿主交界处贴合。
无缝线和无胶的 T-FALK 可能是治疗浅层前角膜瘢痕的最佳方法,可获得良好的视力结果。