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[大动脉转位Jatene手术后的心脏功能:特别提及术后瓣上肺动脉狭窄]

[Cardiac performance before and after Jatene procedure for transposition of the great arteries: with specific reference to post-operative supravalvular pulmonary stenosis].

作者信息

Tsuda E, Ono Y, Arakaki Y, Echigo S, Fukushima H, Takahashi O, Kamiya T, Yagihara T

机构信息

Department of Pediatrics, National Cardiovascular Center, Suita.

出版信息

J Cardiol. 1991;21(1):141-50.

PMID:1817172
Abstract

The cardiac performance was evaluated in patients who had received arterial switch operation (AS-op) for transposition of the great arteries (TGA) in their infancy with special attention to postoperative supravalvular pulmonary stenosis (SVPS). AS-op was performed in 36 infants; 13 with simple TGA and 23 with TGA accompanied with ventricular septal defect. Nine patients had undergone pulmonary arterial banding with systemico-pulmonary shunt. The mean age at surgery was 7 months. Postoperative catheterization was performed on average of 15 months after surgery. The end-diastolic volume (EDV) and ejection fraction (EF) of the left and right ventricles (LV, RV) were calculated from biplane cineangiograms. LVEDV and RVEDV were normalized and expressed as % of normals. SVPS was defined as peak systolic pressure gradient of 50 mmHg or higher between the RV and the pulmonary artery (PA). The mean LVEDV, RVEDV, LVEF and RVEF values were all within the normal range. Inverse correlation was observed between the peak systolic RV-PA pressure gradient and RVEF (n = 29, r = -0.84, p less than 0.001). SVPS after AS-op was observed in 8 patients (22%). Stenosis was observed at the site of anastomosis of the artery. In these cases, the diameter of the PA at the stenotic site decreased to 52% of the preoperative values. Branch stenosis of the PA was observed in 3 patients who had undergone surgery during the neonatal period. Generally, the results after AS-op were satisfactory in terms of cardiac performance. Postoperative SVPS was observed in 8 patients (22%) with decreased RVEF. Careful observations of the growth of PA after AS-op are mandatory.

摘要

对婴儿期接受大动脉转位(TGA)动脉调转术(AS-op)的患者的心脏功能进行评估,特别关注术后的瓣上肺动脉狭窄(SVPS)。36例婴儿接受了AS-op手术;13例为单纯TGA,23例为合并室间隔缺损的TGA。9例患者曾接受肺动脉环扎并体肺分流术。手术时的平均年龄为7个月。术后平均15个月进行心导管检查。根据双平面心血管造影计算左、右心室(LV、RV)的舒张末期容积(EDV)和射血分数(EF)。LVEDV和RVEDV进行标准化处理,并表示为正常水平的百分比。SVPS定义为RV与肺动脉(PA)之间的收缩期峰值压力梯度≥50 mmHg。LVEDV、RVEDV、LVEF和RVEF的平均值均在正常范围内。观察到收缩期RV-PA峰值压力梯度与RVEF呈负相关(n = 29,r = -0.84,p < 0.001)。8例患者(22%)术后出现SVPS。在动脉吻合部位观察到狭窄。在这些病例中,狭窄部位的PA直径降至术前值的52%。3例新生儿期接受手术的患者观察到PA分支狭窄。总体而言,就心脏功能而言,AS-op术后的结果令人满意。8例患者(22%)术后出现SVPS,RVEF降低。AS-op术后必须仔细观察PA的生长情况。

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