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体外冲击波碎石术(ESWL)治疗胰管结石的基础与临床研究

[Fundamental and clinical studies of extracorporeal shock wave lithotripsy (ESWL) for pancreatic duct stones].

作者信息

Ohara H, Gotoh K, Noguchi Y, Hoshino M

机构信息

Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 1991 Dec;88(12):2861-70.

PMID:1817196
Abstract

The application of ESWL for pancreatic duct stones was studied clinically, and the safety of this technique was also investigated experimentally. In 12 patients suffering from chronic pancreatitis and having calcified stones in the main pancreatic duct, ESWL was performed. None of the patient had received endoscopic pancreatic sphincterotomy before ESWL. Stone disintegration was obtained in all cases, and the main pancreatic duct stones completely disappeared in 9 of 12 cases. As a result, not only exacerbation of pancreatitis was removed, but also the preservation of pancreatic endocrine and exocrine functions was suggested. With regard to complications, no abnormalities were observed experimentally in the pancreatic parenchyma of treated dogs, and similarly no acute symptoms were recognized in the patients with pancreatic duct stones. ESWL for pancreatic duct stones is low in stress for the patient, and is effective for large stones. We therefore conclude that ESWL might be an extremely useful, new non-surgical treatment approach to control of pancreatic duct stones.

摘要

对体外冲击波碎石术(ESWL)治疗胰管结石进行了临床研究,并对该技术的安全性进行了实验研究。对12例患有慢性胰腺炎且主胰管有钙化结石的患者进行了ESWL治疗。所有患者在ESWL治疗前均未接受过内镜下胰管括约肌切开术。所有病例结石均被击碎,12例中有9例主胰管结石完全消失。结果,不仅消除了胰腺炎的加重,而且提示保留了胰腺的内分泌和外分泌功能。关于并发症,在接受治疗的犬的胰腺实质中未观察到实验异常,同样,胰管结石患者也未出现急性症状。ESWL治疗胰管结石对患者的应激较小,对大结石有效。因此,我们得出结论,ESWL可能是一种极其有用的新型非手术治疗方法,用于控制胰管结石。

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