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单次应用体外冲击波碎石术是胰管结石患者的首选治疗方法。

Single application extracorporeal shock wave lithotripsy is the first choice for patients with pancreatic duct stones.

作者信息

Ohara H, Hoshino M, Hayakawa T, Kamiya Y, Miyaji M, Takeuchi T, Okayama Y, Gotoh K

机构信息

First Department of Internal Medicine, Nagoya City University Medical School, Japan.

出版信息

Am J Gastroenterol. 1996 Jul;91(7):1388-94.

PMID:8678001
Abstract

OBJECTIVES

We performed extracorporeal shock wave lithotripsy (ESWL) as the treatment of first choice on 32 chronic pancreatitis patients with main pancreatic duct (MPD) stones prospectively to establish more convenient and safer treatment.

METHODS

All patients were treated in a prone position, and shock waves were discharged from the ventral side. ESWL was performed once or twice a week, and no other treatments before ESWL had been applied.

RESULTS

Disintegration of all MPD stones to 3 mm or less in diameter could be achieved in all treated patients. Complete clearance of the stones was obtained in 24 patients (75%) without the necessity of endoscopic extraction of fragments. Reduction of MPD diameters after ESWL was statistically significant (p < 0.01). Epigastric and/or back pain complaints before ESWL were completely alleviated in 79% (periods of follow-up: 16-63 months, mean 44), and the pancreatic exocrine function also improved in 61%. No severe complications occurred in any of the patients.

CONCLUSIONS

ESWL, which is comparatively easy to perform, is a safe and efficient approach that changes endoscopy's status as an indispensable pretreatment. Therefore, ESWL can be recommended as the first choice treatment for patients with chronic pancreatitis accompanied by MPD stones that should be tried before consideration of either surgical or endoscopic procedures.

摘要

目的

我们前瞻性地对32例伴有主胰管(MPD)结石的慢性胰腺炎患者采用体外冲击波碎石术(ESWL)作为首选治疗方法,以建立更便捷、更安全的治疗方式。

方法

所有患者均取俯卧位,冲击波从腹侧释放。ESWL每周进行1次或2次,在进行ESWL之前未应用其他治疗方法。

结果

所有接受治疗的患者均可将所有MPD结石碎裂至直径3mm或更小。24例患者(75%)结石完全清除,无需内镜下取出碎片。ESWL后MPD直径缩小具有统计学意义(p<0.01)。79%的患者ESWL前的上腹部和/或背部疼痛主诉完全缓解(随访时间:16 - 63个月,平均44个月),61%的患者胰腺外分泌功能也得到改善。所有患者均未发生严重并发症。

结论

ESWL操作相对简便,是一种安全有效的治疗方法,改变了内镜作为必不可少的预处理手段的地位。因此,对于伴有MPD结石的慢性胰腺炎患者,在考虑手术或内镜治疗之前,ESWL可作为首选治疗方法推荐尝试。

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