Suppr超能文献

创伤中心护理对严重下肢创伤后功能结局的影响。

The impact of trauma-center care on functional outcomes following major lower-limb trauma.

作者信息

Mackenzie Ellen J, Rivara Frederick P, Jurkovich Gregory J, Nathens Avery B, Egleston Brian L, Salkever David S, Frey Katherine P, Scharfstein Daniel O

机构信息

Johns Hopkins Bloomberg School of Public Health, 624 North Broadway, Room 462, Baltimore, MD 21205, USA.

出版信息

J Bone Joint Surg Am. 2008 Jan;90(1):101-9. doi: 10.2106/JBJS.F.01225.

Abstract

BACKGROUND

Although studies have shown that treatment at a trauma center reduces a patient's risk of dying following major trauma, important questions remain as to the effect of trauma centers on functional outcomes, especially among patients who have sustained major lower-limb trauma.

METHODS

Domain-specific scores on the Medical Outcomes Study Short Form Health Survey (SF-36) supplemented by scores on the mobility subscale of the Musculoskeletal Function Assessment (MFA) and the Revised Center for Epidemiologic Studies Depression Scale (CESD-R) were compared among patients treated in eighteen hospitals with a level-I trauma center and fifty-one hospitals without a trauma center. Included in the study were 1389 adults, eighteen to eighty-four years of age, with at least one lower-limb injury with a score of >/=3 points according to the Abbreviated Injury Scale (AIS). To account for the competing risk of death, we estimated the survivors' average causal effect. Estimates were derived for all patients with a lower-limb injury and separately for a subset of patients without associated injuries of the head or spinal cord.

RESULTS

For patients with a lower-limb injury resulting from a high-energy force, care at a trauma center yielded modest but clinically meaningful improvements in physical functioning and overall vitality at one year after the injury. After adjustment for differences in case mix and the competing risk of death, the average differences in the SF-36 physical functioning and vitality scores and the MFA mobility score were 7.82 points (95% confidence interval: 2.65, 12.98), 6.80 points (95% confidence interval: 2.53, 11.07), and 6.31 points (95% confidence interval: 0.25, 12.36), respectively. These results were similar when the analysis was restricted to patients without associated injuries to the head or spine. Treatment at a trauma center resulted in negligible differences in outcome for the subset of patients with injuries resulting from low-energy forces.

CONCLUSIONS

This study provides evidence that patients who sustain high-energy lower-limb trauma benefit from treatment at a level-I trauma center.

摘要

背景

尽管研究表明,在创伤中心接受治疗可降低严重创伤患者的死亡风险,但创伤中心对功能结局的影响仍存在重要问题,尤其是在遭受严重下肢创伤的患者中。

方法

比较了在18家设有一级创伤中心的医院和51家没有创伤中心的医院接受治疗的患者在医学结局研究简明健康调查(SF - 36)上的特定领域得分,并辅以肌肉骨骼功能评估(MFA)活动度子量表得分和修订的流行病学研究中心抑郁量表(CESD - R)得分。该研究纳入了1389名年龄在18至84岁之间的成年人,他们至少有一处下肢损伤,根据简略损伤量表(AIS)得分≥3分。为了考虑死亡的竞争风险,我们估计了幸存者的平均因果效应。对所有下肢损伤患者以及没有头部或脊髓相关损伤的患者子集分别进行了估计。

结果

对于因高能量暴力导致下肢损伤的患者,在创伤中心接受治疗在受伤后一年的身体功能和总体活力方面产生了适度但具有临床意义的改善。在调整病例组合差异和死亡竞争风险后,SF - 36身体功能和活力得分以及MFA活动度得分的平均差异分别为7.82分(95%置信区间:2.65,12.98)、6.80分(95%置信区间:2.53,11.07)和6.31分(95%置信区间:0.25,12.36)。当分析仅限于没有头部或脊柱相关损伤的患者时,结果相似。对于因低能量暴力导致损伤的患者子集,在创伤中心接受治疗的结局差异可忽略不计。

结论

本研究提供了证据,表明遭受高能量下肢创伤的患者从一级创伤中心的治疗中获益。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验