Datta Sayan, Foss Alexander J E, Grainge Matthew J, Gregson Richard M, Zaman Anwar, Masud Tahir, Osborn Fran, Harwood Rowan H
Department of Ophthalmology, Queen's Medical Centre, Nottingham, United Kingdom.
Invest Ophthalmol Vis Sci. 2008 Jan;49(1):1-6. doi: 10.1167/iovs.06-1073.
To investigate the relative contribution of visual and other factors to quality of life among elderly women with bilateral cataract.
Data were analyzed from a trial of first-eye cataract surgery. Visual parameters, general health, and social variables, and disease-specific (VF-14 Index of Visual Function), generic (Euroqol: EQ-5D, London Handicap Scale, Barthel), and intermediate (anxiety, depression, and activity) outcomes were measured at baseline and 6 months later, when approximately half the group had had surgery.
Three hundred six participants provided data at baseline, and 289 at 6 months. At baseline, acuity, stereopsis, and contrast sensitivity were all associated with quality of life. Acuity and stereopsis were most strongly and consistently associated. Change in VF-14 was associated with changes in stereopsis and contrast sensitivity, while change in handicap was associated with change in stereopsis.
Acuity, stereopsis, and contrast sensitivity each contributed to quality of life, across a range of measures, in elderly women with cataract. Acuity was marginally the most consistently and generally the most strongly associated, but in some analyses stereopsis was more important. Change in quality of life was associated with change in stereopsis and contrast sensitivity.
探讨视觉因素和其他因素对双侧白内障老年女性生活质量的相对影响。
对一项单眼白内障手术试验的数据进行分析。在基线时以及六个月后（此时约一半患者已接受手术）测量视觉参数、总体健康状况以及社会变量，同时测量特定疾病（视觉功能VF - 14指数）、通用（欧洲五维度健康量表：EQ - 5D、伦敦残疾量表、巴氏指数）和中间指标（焦虑、抑郁和活动能力）。
306名参与者在基线时提供了数据，289名在六个月后提供了数据。在基线时，视力、立体视觉和对比敏感度均与生活质量相关。视力和立体视觉的相关性最强且最为稳定。VF - 14的变化与立体视觉和对比敏感度的变化相关，而残疾程度的变化与立体视觉的变化相关。
在患有白内障的老年女性中，视力、立体视觉和对比敏感度在一系列测量指标中均对生活质量有影响。视力在一定程度上是最稳定且通常相关性最强的因素，但在某些分析中，立体视觉更为重要。生活质量的变化与立体视觉和对比敏感度的变化相关。
