Nuotio Maria, Tammela Teuvo L J, Luukkaala Tiina, Jylhä Marja
Geriatric Unit, South-Ostrobothnia Hospital District, Seinäjoki Central Hospital, Seinäjoki, Finland.
Aging Clin Exp Res. 2007 Dec;19(6):465-71. doi: 10.1007/BF03324732.
Lower urinary tract symptoms (LUTS) with comorbidities are common in old age. The aim here was to investigate the associations of urgency symptoms with self-rated health, mood and functioning in a random older population adjusted for comorbid conditions.
A population-based cross-sectional survey was made involving 343 people (159 men and 184 women) aged 70 years and over. LUTS were categorized as symptoms with or without urgency. Perceived inconvenience from LUTS, self-rated health, mood, social activity and activities of daily living (ADL), instrumental activities of daily living (IADL) and mobility disability were the outcome measures. Ageand gender-adjusted and multivariate logistic regression models were constructed in order to examine the associations of urgency and non-urgency symptoms with the outcomes. The covariates were age, gender, and self-reported cardiovascular, musculoskeletal, neurological and other chronic diseases.
Perceived inconvenience from urgency symptoms was more frequent than that from non-urgency symptoms (64% vs 20%, p<0.001). In the age- and gender-adjusted logistic regression models, LUTS with urgency were associated with poor self-rated health (OR [odds ratio] 2.35; 95% CI [confidence interval] 1.06-5.20), depressive mood (OR 7.29; 95% CI 2.91-18.30), ADL (OR 2.33; 95% CI 1.10-4.92), IADL (OR 2.16; 95% CI 1.19-3.92) and mobility disability (OR 2.44; 95% CI 1.37-4.36). LUTS without urgency were associated with depressive mood (OR 5.02; 95% CI 1.97-12.82) and mobility disability (OR 1.97; 95% CI 1.10-3.53). In the multivariate analyses in which comorbid conditions were added to the model, the associations of non-urgency and urgency symptoms persisted only with depressive mood (OR 4.00; 95% CI 1.52-10.53 and OR 6.16; 95% CI 2.39-15.84, respectively).
Urgency symptoms are associated with poor self-rated health, depressive mood and disability in older people. There is an independent association between both urgency and non-urgency LUTS and depressive mood. A careful assessment of the mental state of older individuals with LUTS is warranted.
伴有合并症的下尿路症状（LUTS）在老年人中很常见。本研究旨在调查在调整合并症的随机老年人群中，尿急症状与自评健康状况、情绪及功能之间的关联。
进行了一项基于人群的横断面调查，涉及343名70岁及以上的人群（159名男性和184名女性）。LUTS被分类为有或无尿急症状。LUTS带来的感知不便、自评健康状况、情绪、社交活动以及日常生活活动（ADL）、工具性日常生活活动（IADL）和行动能力障碍为观察指标。构建年龄和性别调整以及多因素逻辑回归模型，以检验尿急和非尿急症状与观察指标之间的关联。协变量包括年龄、性别以及自我报告的心血管、肌肉骨骼、神经和其他慢性疾病。
尿急症状带来的感知不便比非尿急症状更常见（64%对20%，p<0.001）。在年龄和性别调整的逻辑回归模型中，伴有尿急的LUTS与自评健康状况差（比值比[OR]2.35；95%置信区间[CI]1.06 - 5.20）、抑郁情绪（OR 7.29；95% CI 2.91 - 18.30）、ADL（OR 2.33；95% CI 1.10 - 4.92）、IADL（OR 2.16；95% CI 1.19 - 3.92）和行动能力障碍（OR 2.44；95% CI 1.37 - 4.36）相关。无尿急的LUTS与抑郁情绪（OR 5.02；95% CI 1.97 - 12.82）和行动能力障碍（OR 1.97；95% CI 1.10 - 3.53）相关。在将合并症纳入模型的多因素分析中，非尿急和尿急症状仅与抑郁情绪仍存在关联（分别为OR 4.00；95% CI 1.52 - 10.53和OR 6.16；95% CI 2.39 - 十五点八四）。
尿急症状与老年人自评健康状况差、抑郁情绪和残疾相关。尿急和非尿急的LUTS与抑郁情绪均存在独立关联。对患有LUTS的老年人的精神状态进行仔细评估是必要的。
