Tikar S N, Mendki M J, Chandel K, Parashar B D, Prakash Shri
Defence Research and Development Establishment, Defence R&D Organization, Jhansi Road, Gwalior 474002, India.
Parasitol Res. 2008 Apr;102(5):907-13. doi: 10.1007/s00436-007-0848-5. Epub 2008 Jan 4.
Susceptibility of Aedes aegypti to some insecticides in different geographic areas was conducted during dengue and chikungunya outbreak. At present, the only method of preventing dengue and chikungunya is to control the vector, which is the weakest link in vector-borne diseases. In our study, the susceptibility of A. aegypti collected from urban areas of Delhi, Mumbai, Jodhpur, Chennai and Coimbatore was evaluated against temephos, fenthion, malathion and DDT. The A. aegypti from different locations exhibited 0.33-7.11, 0.36-3.00, 0.65-2.84 and 2.16-20.8 fold more lethal concentration value of 50% (LC50) to temephos, fenthion, malathion and DDT, respectively, compared to susceptible reference strain. The result reveals that A. aegypti from various locations studied are still susceptible to temephos, fenthion and malathion, whereas low level of DDT resistance was noticed in field-collected A. aegypti. Amongst the insecticides tested, temephos was found to be relatively more effective in controlling A. aegypti, followed by fenthion, malathion and DDT.
在登革热和基孔肯雅热疫情期间，对不同地理区域的埃及伊蚊对某些杀虫剂的敏感性进行了研究。目前，预防登革热和基孔肯雅热的唯一方法是控制病媒，而病媒是媒介传播疾病中最薄弱的环节。在我们的研究中，评估了从德里、孟买、焦特布尔、金奈和哥印拜陀市区采集的埃及伊蚊对杀螟硫磷、倍硫磷、马拉硫磷和滴滴涕的敏感性。与敏感参考品系相比，来自不同地点的埃及伊蚊对杀螟硫磷、倍硫磷、马拉硫磷和滴滴涕的半数致死浓度值（LC50）分别高出0.33 - 7.11倍、0.36 - 3.00倍、0.65 - 2.84倍和2.16 - 20.8倍。结果表明，所研究的不同地点的埃及伊蚊对杀螟硫磷、倍硫磷和马拉硫磷仍敏感，而在野外采集的埃及伊蚊中发现了低水平的滴滴涕抗性。在所测试的杀虫剂中，杀螟硫磷被发现对控制埃及伊蚊相对更有效，其次是倍硫磷、马拉硫磷和滴滴涕。
