Hasanbegović Edo
Pedijatrijska klinika, Klinicki centar Univerziteta Sarajevo, Blonicka.
Med Arh. 2006;60(6 Suppl 2):84-6.
to present main clinical and hematologic features of pediatric leukemias treated at Hematooncologic department of Pediatric Clinic in Sarajevo during last 7 years.
In retrospective study we followed up children with leukemia aged 0-15 who were treated during period of 01.01.1997-31.12.2003. at Hematooncologic department on Pediatric Clinic in Sarajevo.
A total number of patient with leukemia was 130 of them 112 (83.2%) had acute lymphoblastic leukemia (ALL), 16 (12.3%) of them had acute myeloid leukemia (AML) and 2 (1.5%) patients had chronic myeloid leukemia (CML). There were 84 (64.6%) boys and 46 (35.4%) girls. Median age of newly diagnosed patients was 6 years and 4 months. Dominant clinical signs were: high temperature-72.9%, fatigue and paleness-74.8% and bone pain-87.9%. Most of the children had leucocitosis (51.5%), anemia (56.1%) and trombocitopenia (57.5%).
Most frequent signs at the beginning of the illness are general symptoms like fatigue, unclear febrile state and accented bone pains. Those united signs with complete blood picture finding should be enough reason for suspicion under possible leukemia.
呈现过去7年在萨拉热窝儿科诊所血液肿瘤科接受治疗的儿童白血病的主要临床和血液学特征。
在一项回顾性研究中，我们对1997年1月1日至2003年12月31日期间在萨拉热窝儿科诊所血液肿瘤科接受治疗的0至15岁白血病患儿进行了随访。
白血病患者总数为130例，其中112例（83.2%）患有急性淋巴细胞白血病（ALL），16例（12.3%）患有急性髓细胞白血病（AML），2例（1.5%）患有慢性髓细胞白血病（CML）。有84名（64.6%）男孩和46名（35.4%）女孩。新诊断患者的中位年龄为6岁4个月。主要临床体征为：高热 - 72.9%，乏力和面色苍白 - 74.8%，骨痛 - 87.9%。大多数儿童有白细胞增多（51.5%）、贫血（56.1%）和血小板减少（57.5%）。
疾病初期最常见的体征是疲劳、不明原因发热状态和明显骨痛等一般症状。这些综合体征以及全血细胞检查结果应足以引起对可能患白血病的怀疑。
