Hasanbegović Edo, Bijedić Vildan, Mehadzić Senada
Pedijatrijska klinika, Klinicki centar Univerziteta u Sarajevu.
Med Arh. 2002;56(3 Suppl 1):33-5.
To determine the diagnostic and prognostic value the bone marrow aspiration in children with severe deficiency anaemia.
In this retrospective study we analysed 75 children 0-4 years of age who were diagnosed and treated from severe anaemia (Hb < 8g/dl) at Haematologic outpatient and hospital department of Pediatric Clinic in Sarajevo in period of 01.01.1999. to 31.12.1999.
We analyzed totally 75 children--37 (49.33%) boys and 38 (50.67%) girls. Morphologic finding of bone marrow aspirate smear showed: features of ferriprive flora in 24% of analyzed patients; dimorphic bone marrow features in 9.3% of patients; feriprivic flora with dyshematopoesis in 62.7% and megaloblasic anaemia features in 1.3% of analyzed patients. In two children we diagnosed leukemias from bone marrow aspirate; one was ALL/L2 and the second was AML/M2 leukemia.
The most frequent found features of bone marrow aspirate were: feriprivic flora with dyshematopoesis. There was only one case of the megaloblastic bone marrow. But, the finding of dymorphic bone marrow indicated to pluricareny of ethiologic factors for beginning severe nutrititive anaemia. Special value of this paper was discovering of two cases of leukemia by the bone marrow aspirate analysis.
确定骨髓穿刺术在重度贫血患儿中的诊断和预后价值。
在这项回顾性研究中，我们分析了1999年1月1日至1999年12月31日期间在萨拉热窝儿科诊所血液科门诊及住院部诊断和治疗的75名0至4岁重度贫血（血红蛋白<8g/dl）患儿。
我们共分析了75名患儿，其中37名（49.33%）为男孩，38名（50.67%）为女孩。骨髓穿刺涂片的形态学检查结果显示：24%的分析患者有缺铁性细胞形态特征；9.3%的患者有双形性骨髓特征；62.7%的患者有缺铁性细胞形态特征伴造血异常，1.3%的分析患者有巨幼细胞贫血特征。我们从两名患儿的骨髓穿刺中诊断出白血病，一名为急性淋巴细胞白血病/L2型，另一名为急性髓系白血病/M2型。
骨髓穿刺最常见的特征是：缺铁性细胞形态特征伴造血异常。仅有1例巨幼细胞性骨髓病例。但是，双形性骨髓的发现提示重度营养性贫血病因的多元性。本文的特殊价值在于通过骨髓穿刺分析发现了2例白血病病例。
