Majumder S, Mandal S K, Chowdhury S Roy, Bandyopadhyay D, Bandyopadhyay R, Chakraborty P P
Department of Medicine, Medical College, Kolkat.
J Assoc Physicians India. 2007 Oct;55:737-8.
A 19-year male presented with acute onset, gradually progressive symmetric indurations involving the skin over the face, neck, shoulders and upper part of chest following an upper respiratory tract infection. Detailed history and examination did not reveal evidence of Raynauds' phenomenon, nail changes, digital ulcers, pigmentation or any systemic involvement. Autoantibodies for systemic sclerosis were absent. Histopathology of skin biopsy documented scleredema. Antistreptolysin O (ASO) titer was elevated. We diagnosed a case of Scleredema adultorum of Buschke following a streptococcal throat infection. We report this case to highlight the importance of clinically differentiating this relatively benign, self-limiting disorder from systemic sclerosis.
一名19岁男性，在上呼吸道感染后，出现急性起病，逐渐进展的对称性硬结，累及面部、颈部、肩部及胸部上半部分皮肤。详细的病史询问和体格检查未发现雷诺现象、指甲改变、指端溃疡、色素沉着或任何全身受累的证据。未检测到系统性硬化症的自身抗体。皮肤活检的组织病理学证实为硬化性水肿。抗链球菌溶血素O（ASO）滴度升高。我们诊断该病例为链球菌性咽炎感染后发生的Buschke成人硬化性水肿。我们报告此病例以强调临床上将这种相对良性、自限性疾病与系统性硬化症相鉴别的重要性。
