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三叉神经所有三个分支的营养综合征:一种脑部手术后未被充分认识的并发症。

Trigeminal trophic syndrome of all three nerve branches: an underrecognized complication after brain surgery.

作者信息

Luksić Ivica, Luksić Ivana, Sestan-Crnek Sandra, Virag Mihajlo, Macan Darko

机构信息

1 Department of Maxillofacial and Oral Surgery, University Hospital Dubrava, Medical School and School of Dental Medicine, University of Zagreb, Croatia.

出版信息

J Neurosurg. 2008 Jan;108(1):170-3. doi: 10.3171/JNS/2008/108/01/0170.

Abstract

The authors report a case of trigeminal trophic syndrome (TTS) that occurred as a complication of a neurosurgical procedure. Three years after a second surgical treatment for a meningioma of the cerebellopontine angle, this 32-year-old woman developed TTS with progressive skin ulcers on the left ala nasi and the left side of the forehead and chin. Trigeminal trophic syndrome is an extremely rare cause of facial ulceration. It occurs as a consequence of trigeminal nerve damage or impaired central sensory connections. To the authors' knowledge, this is the first report of lesions in the dermatomes of all three branches of the nerve after a neurosurgical procedure. Early recognition of this disorder is important, as treatment is difficult and often unsatisfactory. Many clinicians are not aware of this disease, thus, it may be more common than previously thought. The importance of recognizing and diagnosing TTS, as well as its treatment, are discussed.

摘要

作者报告了一例作为神经外科手术并发症发生的三叉神经营养综合征(TTS)。在对桥小脑角脑膜瘤进行第二次手术治疗三年后,这名32岁女性患上了TTS,左侧鼻翼、前额和下巴左侧出现了进行性皮肤溃疡。三叉神经营养综合征是面部溃疡极为罕见的病因。它是三叉神经损伤或中枢感觉连接受损的结果。据作者所知,这是神经外科手术后神经所有三个分支的皮节出现病变的首例报告。尽早识别这种疾病很重要,因为治疗困难且往往效果不佳。许多临床医生并不了解这种疾病,因此,它可能比之前认为的更为常见。文中讨论了识别和诊断TTS的重要性及其治疗方法。

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