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感染性皮炎、人类嗜T细胞病毒1型相关脊髓病和成人T细胞白血病/淋巴瘤的早期序贯发展。

Early sequential development of infective dermatitis, human T cell lymphotropic virus type 1-associated myelopathy, and adult T cell leukemia/lymphoma.

作者信息

Farre Lourdes, de Oliveira Maria de Fátima Paim, Primo Janeusa, Vandamme Anne-Mieke, Van Weyenbergh Johan, Bittencourt Achiléa L

机构信息

Laboratory of Immunoregulation and Microbiology, Centro de Pesquisa Conçalo Moniz-Fundação Oswaldo Cruz, Bahia, Brazil.

出版信息

Clin Infect Dis. 2008 Feb 1;46(3):440-2. doi: 10.1086/524695.

DOI:10.1086/524695
PMID:18173359
Abstract

We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.

摘要

我们描述了一名患有1型人类嗜T细胞病毒（HTLV-1）相关感染性皮炎的患者，该患者在16岁时发展为HTLV-1相关脊髓病/热带痉挛性截瘫以及成人T细胞白血病/淋巴瘤。采用长链反向聚合酶链反应来证明淋巴瘤性皮肤病变中前病毒DNA的单克隆整合。

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