Wong Melissa Hsing Yi, Su Daniel Hsien Wen, Loh Raymond Ser Keat
Department of Ophthalmology, Changi General Hospital, Singapore, Singapore.
Clin Exp Ophthalmol. 2007 Dec;35(9):858-60. doi: 10.1111/j.1442-9071.2007.01605.x.
The authors report a case of nodular scleritis in Sweet's syndrome. The patient was a 40-year-old Malay woman with a history of Sweet's syndrome presented with a 6-day history of a red and painful right eye associated with blurred vision. Clinical examination revealed nodular scleritis of the right eye which was deemed secondary to Sweet's syndrome after investigations for other systemic diseases were negative. The patient demonstrated good response to systemic corticosteroid therapy with complete resolution of scleritis in the right eye. However, her inflammatory skin condition worsened each time the systemic corticosteroids were tapered so colchicine and dapsone were added to treat the dermatologic disease. Ocular manifestations are uncommon in Sweet's syndrome but it is important to diagnose and treat them. This will prevent ocular morbidity and ensure a good clinical outcome.
作者报告了1例伴发Sweet综合征的结节性巩膜炎病例。该患者为一名40岁的马来女性，有Sweet综合征病史，右眼红肿疼痛伴视力模糊6天。临床检查发现右眼结节性巩膜炎，在排除其他全身性疾病后，认为其继发于Sweet综合征。该患者对全身用皮质类固醇治疗反应良好，右眼巩膜炎完全消退。然而，每次全身用皮质类固醇减量时，她的皮肤炎症状况都会恶化，因此加用秋水仙碱和氨苯砜来治疗皮肤病。眼部表现在Sweet综合征中并不常见，但对其进行诊断和治疗很重要。这将预防眼部疾病的发生，并确保良好的临床结局。
