Fontana Luigi, Parente Gabriella, Neri Piergiorgio, Reta Massimo, Tassinari Giorgio
Clin Exp Ophthalmol. 2007 Dec;35(9):871-3. doi: 10.1111/j.1442-9071.2007.01609.x.
A woman with progressive bilateral Mooren's ulcer developed recurrent corneal perforations and melting requiring tectonic grafts, despite conventional immunosuppressant therapy. Following treatment with infliximab, an anti-tumour necrosis factor agent, the patient showed marked reduction in conjunctival inflammation and no further recurrence of corneal thinning and perforation during 2-year follow up on maintaining treatment.
一名患有进行性双侧蚕蚀性角膜溃疡的女性，尽管接受了传统免疫抑制治疗，但仍反复出现角膜穿孔和溶解，需要进行结构性移植。在用抗肿瘤坏死因子药物英夫利昔单抗治疗后，患者结膜炎症明显减轻，在维持治疗的2年随访期间角膜变薄和穿孔未再复发。
