Hatibović-Kofman S, Koch G
Institute for Postgraduate Dental Education, Jönköping, Sweden.
Swed Dent J. 1991;15(6):253-8.
The aims of this study were to investigate in vivo the release of fluoride from three glass ionomer cements (GICs) Vitrebond, Ketac-Fil and ChemFil II into the saliva of preschool children for a 1-year period and also to study in vitro the release-absorption-release of fluoride from the same GICs for 16 weeks. In the first part of the study, glass ionomer restorations were placed in primary teeth in preschool children. Unstimulated saliva was collected and the fluoride in the saliva was measured before placement of the restorations, immediately after, after 3 weeks, after 6 weeks, and after 1 year. In the second part of the study, test specimens of GICs were placed in deionized water and the release of fluoride was measured weekly for 16 weeks. At week 12, samples were exposed to fluoride toothpaste. The concentration of fluoride in saliva was 0.04 ppm before placement of the restorations. After three weeks it had increased to 0.8 ppm and the level remained as high as 0.3 ppm even after 1 year. In the laboratory study the tested glass ionomer cements showed a capacity to absorb fluoride from the fluoride toothpaste and then release it. It is concluded that glass ionomer cement can act as a rechargeable slow release fluoride device.
本研究的目的是在1年时间内，对三种玻璃离子水门汀（GICs）——维他玻璃离子水门汀、Ketac-Fil和ChemFil II——在学龄前儿童唾液中的氟释放情况进行体内研究，同时对相同的玻璃离子水门汀在16周内的氟释放-吸收-再释放情况进行体外研究。在研究的第一部分，将玻璃离子修复体置于学龄前儿童的乳牙中。在修复体放置前、放置后即刻、3周后、6周后和1年后收集未刺激唾液，并测量唾液中的氟含量。在研究的第二部分，将玻璃离子水门汀的测试样本置于去离子水中，每周测量氟释放量，持续16周。在第12周时，将样本暴露于含氟牙膏。修复体放置前唾液中的氟浓度为0.04 ppm。3周后，氟浓度增加到0.8 ppm，即使在1年后，该水平仍高达0.3 ppm。在实验室研究中，测试的玻璃离子水门汀显示出从含氟牙膏中吸收氟然后再释放氟的能力。得出的结论是，玻璃离子水门汀可作为一种可再充电的缓释氟装置。
