活体肝移植术后应用生长抑素成功治疗乳糜性腹水
Successful management of chylous ascites after living donor liver transplantation with somatostatin.
作者信息
Ijichi Hideki, Soejima Yuji, Taketomi Akinobu, Yoshizumi Tomoharu, Uchiyama Hideaki, Harada Noboru, Yonemura Yusuke, Maehara Yoshihiko
机构信息
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
出版信息
Liver Int. 2008 Jan;28(1):143-5. doi: 10.1111/j.1478-3231.2007.01556.x.
Chylous ascites is a rare complication following liver transplantation. A variety of treatment options have been proposed for the management of chylous ascites; however, their effectiveness following a liver transplant is unknown. A 40-year-old woman who underwent living donor liver transplantation for primary biliary cirrhosis developed chylous ascites 21 days after the transplant. A conventional treatment consisting of a low-fat diet with total parenteral nutrition failed to treat the complication for 104 days. However, the use of somatostatin in combination with total parenteral nutrition resulted in a rapid falloff in chyle output without any adverse effects. Somatostatin and total parenteral nutrition are an effective option for the treatment of chylous ascites after living donor liver transplantation.
乳糜性腹水是肝移植术后一种罕见的并发症。针对乳糜性腹水的处理，已经提出了多种治疗方案；然而，这些方案在肝移植后的有效性尚不清楚。一名40岁女性因原发性胆汁性肝硬化接受了活体供肝肝移植，术后21天出现了乳糜性腹水。采用低脂饮食联合全胃肠外营养的传统治疗方法，104天未能治愈该并发症。然而，使用生长抑素联合全胃肠外营养可使乳糜液排出量迅速减少，且无任何不良反应。生长抑素和全胃肠外营养是治疗活体供肝肝移植术后乳糜性腹水的有效选择。
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