Kyra Becker, MD University of Washington, Box 359775 HMC, 325 9th Avenue, Seattle, WA 98104, USA.
Curr Treat Options Neurol. 2007 Nov;9(6):463-9. doi: 10.1007/s11940-007-0047-9.
An obvious treatment goal in patients suffering an acute stroke due to an occlusion of a cerebral vessel is restoring blood flow to ischemic tissue. Studies have shown that recanalization of blood vessels can be achieved through endovascular therapy using either thrombolytics or mechanical clot removal. Because the clinical response to intravenous thrombolysis is exquisitely time-dependent, patients should be treated as soon as possible. Intravenous thrombolysis is the initial therapy in patients who present within 3 hours of stroke onset. Endovascular therapy should be considered for patients with large-vessel occlusions who are not candidates for intravenous thrombolysis or who do not recanalize after intravenous thrombolysis.
对于因脑血管阻塞而导致急性中风的患者，一个明显的治疗目标是恢复缺血组织的血流。研究表明，通过使用溶栓药物或机械血栓清除术的血管内治疗，可以实现血管再通。由于静脉溶栓的临床反应对时间极为敏感，因此应尽快对患者进行治疗。对于在中风发作后 3 小时内就诊的患者，静脉溶栓是初始治疗方法。对于不适合静脉溶栓或静脉溶栓后未再通的大血管闭塞患者，应考虑血管内治疗。
