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吸入性胰岛素治疗患者的选择与教育

Selection and education of patients for inhaled insulin.

作者信息

Bellary Srikanth, Barnett Anthony H

机构信息

Undergraduate Centre, Heart of England NHS Foundation Trust, Bordesley Green East, Birmingham, UK.

出版信息

Curr Diab Rep. 2007 Oct;7(5):363-8. doi: 10.1007/s11892-007-0059-6.

Abstract

Inhaled insulin is a recent advance in insulin delivery that promises to be an effective alternative to subcutaneous insulin. Several insulin delivery systems are currently in development and the first of these has been approved for clinical use. Inhaled insulin offers greater flexibility and convenience for patients with diabetes and may be particularly useful in those who are reluctant to initiate or intensify insulin treatment. Although promising, potential concerns remain regarding its long-term effects on lungs. Also, excluding certain groups of patients such as smokers and those with respiratory illnesses will restrict its use at present. Lack of familiarity with the technology, especially relating to dose adjustments and inhaler device, is also likely to present fresh challenges. But, careful selection of patients, education, and continued support from health professionals is vital to ensure success with this new technology.

摘要

吸入式胰岛素是胰岛素给药领域的一项最新进展,有望成为皮下注射胰岛素的有效替代方法。目前有几种胰岛素给药系统正在研发中,其中第一种已获批用于临床。吸入式胰岛素为糖尿病患者提供了更大的灵活性和便利性,对于那些不愿开始或强化胰岛素治疗的患者可能特别有用。尽管前景广阔,但人们仍对其对肺部的长期影响存在潜在担忧。此外,将某些患者群体(如吸烟者和患有呼吸系统疾病的患者)排除在外,目前会限制其使用。对该技术缺乏熟悉度,尤其是在剂量调整和吸入装置方面,也可能带来新的挑战。但是,仔细挑选患者、进行教育以及健康专业人员的持续支持对于确保这项新技术取得成功至关重要。

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