Nagueh Sherif F
The Methodist DeBakey Heart Center, The Methodist Hospital, Houston, Texas 77030, USA.
J Am Coll Cardiol. 2008 Jan 1;51(1):18-22. doi: 10.1016/j.jacc.2007.08.052.
Myocardial imaging has been successfully applied to the evaluation of patients with heart failure, particularly identifying candidates who are likely to respond to cardiac resynchronization therapy (CRT). Recent studies have shown the benefits of CRT in heart failure patients with depressed ejection fraction (EF) and a narrow QRS complex, albeit in a small number of patients, and without a placebo arm. In addition, few reports have noted the presence of pathophysiologically relevant mechanical dyssynchrony in patients with heart failure and normal EF. Collectively, these data support the need for a better understanding of cardiac function/dysfunction and its treatment in these patient groups.
心肌成像已成功应用于心力衰竭患者的评估，特别是用于识别可能对心脏再同步治疗（CRT）有反应的患者。最近的研究表明，CRT对射血分数（EF）降低且QRS波群狭窄的心力衰竭患者有益，尽管研究对象数量较少且未设安慰剂组。此外，鲜有报告指出EF正常的心力衰竭患者存在病理生理学相关的机械不同步。总体而言，这些数据支持有必要更好地了解这些患者群体的心脏功能/功能障碍及其治疗方法。
