耐抗生素的β-溶血性链球菌
Antibiotic resistant beta-hemolytic streptococci.
作者信息
Lloyd Charmaine A C, Jacob Swarna E, Menon Thangam
机构信息
Dr. A.L. Mudaliar Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, India.
出版信息
Indian J Pediatr. 2007 Dec;74(12):1077-80. doi: 10.1007/s12098-007-0200-1.
OBJECTIVE
An antibiotic-sensitivity study was conducted on 117 strains of group A streptococcus (GAS), 60 strains of group G streptococcus (GGS) and 20 strains of group C streptococcus (GCS) in order to understand current resistance trends.
METHODS
All strains were tested by the Kirby Bauer disc diffusion method to 15 antibiotics. Resistant strains were confirmed by testing the minimum inhibitory concentration (MIC) of antibiotics by broth dilution technique.
RESULTS
Among GAS, highest resistance was observed to tetracycline (27.4%) and erythromycin (16.2%). The GGS and GCS tested, showed similar resistance patterns.
CONCLUSION
All beta-hemolytic streptococci were susceptible to penicillin, amoxycillin, cephalosporins and linezolid. Resistance to erythromycin, tetracycline, clindamycin, chloramphenicol, and quinolones is emerging.
目的
对117株A组链球菌（GAS）、60株G组链球菌（GGS）和20株C组链球菌（GCS）进行抗生素敏感性研究，以了解当前的耐药趋势。
方法
采用 Kirby Bauer 纸片扩散法对所有菌株进行15种抗生素的检测。通过肉汤稀释技术检测抗生素的最低抑菌浓度（MIC）来确认耐药菌株。
结果
在GAS中，对四环素（27.4%）和红霉素（16.2%）的耐药率最高。所检测的GGS和GCS显示出相似的耐药模式。
结论
所有β溶血性链球菌对青霉素、阿莫西林、头孢菌素和利奈唑胺敏感。对红霉素、四环素、克林霉素、氯霉素和喹诺酮类药物的耐药性正在出现。
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