法国儿童中耐大环内酯类化脓性链球菌菌株的出现。
Emergence of macrolide-resistant Streptococcus pyogenes strains in French children.
作者信息
Bingen Edouard, Bidet Philippe, Mihaila-Amrouche Liliana, Doit Catherine, Forcet Samuel, Brahimi Naïma, Bouvet Anne, Cohen Robert
机构信息
Université Denis Diderot-Paris 7, Service de Microbiologie, Hôpital Robert Debré, 48 Bd Sérurier, 75019 Paris, France.
出版信息
Antimicrob Agents Chemother. 2004 Sep;48(9):3559-62. doi: 10.1128/AAC.48.9.3559-3562.2004.
Abstract
We studied the antimicrobial susceptibility of 322 Streptococcus pyogenes throat isolates from French children and their serotype and genomic diversity. A total of 22.4% were erythromycin resistant, and 69.4, 4.2, and 26.4% of these isolates harbored ermB, ermA, and mefA, respectively. Increasing resistance in France is mainly associated with a few emm type 28 clones.
摘要
我们研究了来自法国儿童的322株化脓性链球菌咽喉分离株的抗菌药敏性及其血清型和基因组多样性。共有22.4%的分离株对红霉素耐药，其中分别有69.4%、4.2%和26.4%的分离株携带ermB、ermA和mefA。法国耐药性增加主要与少数emm28型克隆有关。
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