Otberg Nina, Wu Wen-Yu, McElwee Kevin John, Shapiro Jerry
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.
Skinmed. 2008 Jan-Feb;7(1):19-26. doi: 10.1111/j.1540-9740.2007.07163.x.
In this 2-part article, the authors review the primary cicatricial alopecias. Primary cicatricial alopecia can be defined as predominantly lymphocytic, neutrophilic, or mixed based on the nature of the follicular infiltrate that is present around affected hair follicles. Lymphocytic primary cicatricial alopecias include chronic cutaneous lupus erythematosus (discoid lupus erythematosus), lichen planopilaris, classic pseudopelade of Brocq, central centrifugal cicatricial alopecia, alopecia mucinosa, and keratosis follicularis spinulosa decalvans. In this first part, the authors summarize the classification, epidemiology, diagnostic approach, and patient management of lymphocytic cicatricial alopecias. In part II, the authors will focus on neutrophilic cicatricial alopecias and mixed cicatricial alopecias.
在这篇分两部分的文章中，作者回顾了原发性瘢痕性脱发。原发性瘢痕性脱发可根据受累毛囊周围滤泡浸润的性质，主要分为淋巴细胞性、中性粒细胞性或混合性。淋巴细胞性原发性瘢痕性脱发包括慢性皮肤红斑狼疮（盘状红斑狼疮）、扁平苔藓性毛发角化病、经典的布罗克假性斑秃、中央离心性瘢痕性脱发、黏液性脱发和棘状毛囊角化病秃发。在第一部分，作者总结了淋巴细胞性瘢痕性脱发的分类、流行病学、诊断方法和患者管理。在第二部分，作者将重点讨论中性粒细胞性瘢痕性脱发和混合性瘢痕性脱发。
