Smulyan Harold, Sheehe Paul R, Safar Michel E
Department of Medicine, Upstate Medical University, State University of New York, Syracuse, New York, USA.
Am J Hypertens. 2008 Feb;21(2):166-71. doi: 10.1038/ajh.2007.45. Epub 2008 Jan 3.
The brachial artery (BA) mean blood pressure (MBP) is now readily available using the oscillometric technique. In contrast to the auscultatory method where MBP is calculated from the systolic (SBP) and diastolic blood pressure (DBP), oscillometric MBP is measured separately from either SBP or DBP. Because the peripheral MBP is free of amplification, it is nearly the same throughout the entire arterial tree and could represent the corresponding aortic pressure. The oscillometric brachial MBP could therefore serve as a surrogate for aortic MBP and might be a valuable non-invasive risk predictor.
This study compares the oscillometric BA pressures with simultaneously and directly recorded aortic pressures in 100 patients.
These results show that, over a wide range of cuff pressures, the oscillometric MBP, whether alone or with age in multiple regression, predicts aortic pressure better than the SBP or DBP do, with a better correlation coefficient (r = +0.91), low aortic-cuff MBP difference (-0.79 mm Hg) and the lowest s.d. of the individual differences (+7.2 mm Hg).
These results are preliminary and need to be confirmed by larger studies. If confirmed, the predicted aortic pressures should be calculated and displayed by the oscillometric BP devices, the goal being to develop better non-invasive cardiovascular (CV) risk predictors.
使用示波法现在可以很容易地获得肱动脉(BA)平均血压(MBP)。与通过收缩压(SBP)和舒张压(DBP)计算MBP的听诊法不同,示波法MBP是独立于SBP或DBP进行测量的。由于外周MBP不存在放大作用,在整个动脉树中几乎相同,并且可以代表相应的主动脉压力。因此,示波法肱动脉MBP可以作为主动脉MBP的替代指标,可能是一种有价值的非侵入性风险预测指标。
本研究比较了100例患者的示波法肱动脉血压与同时直接记录的主动脉血压。
这些结果表明,在较宽的袖带压力范围内,示波法MBP,无论是单独使用还是在多元回归中结合年龄,预测主动脉压力的效果都优于SBP或DBP,具有更好的相关系数(r = +0.91)、较低的主动脉-袖带MBP差值(-0.79 mmHg)和个体差异的最低标准差(+7.2 mmHg)。
这些结果是初步的,需要更大规模的研究来证实。如果得到证实,示波法血压设备应计算并显示预测的主动脉压力,目标是开发更好的非侵入性心血管(CV)风险预测指标。