Calabrò R S, Savica R, Laganà A, Magaudda A, Imbesi D, Gallitto G, La Spina P, Musolino R
Department of Neurosciences Neurological Division, University of Messina, Messina, Italy.
Neurol Sci. 2007 Dec;28(6):336-8. doi: 10.1007/s10072-007-0849-2. Epub 2008 Jan 4.
A 76-year-old patient, since the age of 45, presented with frequent attacks often triggered by emotional stimuli and characterised by forward head drop and a fall to the ground without loss of consciousness. Clinically these episodes were misinterpreted as pseudoseizures and treated with clomipramine for more than 20 years. In spite of this chronic therapy, during the last year, the attacks presented with a daily recurrence and, moreover, after arbitrary clomipramine withdrawal, they increased in frequency until they became subcontinuous. Videopolygraphic analysis, multiple sleep latency test (MSLT) and human leukocyte antigen (HLA) association studies were suggestive of narcolepsy and the recurrent episodes, diagnosed as status cataplecticus, recovered after citalopram administration.
一名76岁的患者，自45岁起，经常因情绪刺激而发作，表现为头部前倾摔倒在地且无意识丧失。临床上这些发作被误诊为假性癫痫，并使用氯米帕明治疗了20多年。尽管进行了长期治疗，但在过去一年中，发作每天都会复发，而且在随意停用氯米帕明后，发作频率增加直至变得几乎持续不断。视频多导睡眠图分析、多次睡眠潜伏期试验（MSLT）和人类白细胞抗原（HLA）关联研究提示发作性睡病，而被诊断为猝倒状态的反复发作在服用西酞普兰后得到缓解。
