蜡样芽孢杆菌溶血素BL的B组分的X射线晶体结构。
X-ray crystal structure of the B component of Hemolysin BL from Bacillus cereus.
作者信息
Madegowda Mahendra, Eswaramoorthy Subramaniam, Burley Stephen K, Swaminathan Subramanyam
机构信息
Biology Department, Brookhaven National Laboratory, Upton, New York 11973, USA.
出版信息
Proteins. 2008 May 1;71(2):534-40. doi: 10.1002/prot.21888.
Abstract
Bacillus cereus Hemolysin BL enterotoxin, a ternary complex of three proteins, is the causative agent of food poisoning and requires all three components for virulence. The X-ray structure of the binding domain of HBL suggests that it may form a pore similar to other soluble channel forming proteins. A putative pathway of pore formation is discussed.
摘要
蜡样芽孢杆菌溶血素BL肠毒素是一种由三种蛋白质组成的三元复合物，是食物中毒的病原体，其毒性需要所有三种成分。HBL结合结构域的X射线结构表明，它可能形成一个类似于其他可溶性通道形成蛋白的孔。文中讨论了一种假定的孔形成途径。
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