Madegowda Mahendra, Eswaramoorthy Subramaniam, Burley Stephen K, Swaminathan Subramanyam
Biology Department, Brookhaven National Laboratory, Upton, New York 11973, USA.
Proteins. 2008 May 1;71(2):534-40. doi: 10.1002/prot.21888.
Bacillus cereus Hemolysin BL enterotoxin, a ternary complex of three proteins, is the causative agent of food poisoning and requires all three components for virulence. The X-ray structure of the binding domain of HBL suggests that it may form a pore similar to other soluble channel forming proteins. A putative pathway of pore formation is discussed.
蜡样芽孢杆菌溶血素BL肠毒素是一种由三种蛋白质组成的三元复合物，是食物中毒的病原体，其毒性需要所有三种成分。HBL结合结构域的X射线结构表明，它可能形成一个类似于其他可溶性通道形成蛋白的孔。文中讨论了一种假定的孔形成途径。
