Alvero Ayesha B, Montagna Michele K, Mor Gil
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA.
Methods Mol Biol. 2008;414:79-82. doi: 10.1007/978-1-59745-339-4_7.
The immediate assessment of response to therapy is most beneficial to ovarian cancer patients. This study shows the correlation of drug-induced caspase activation determined by western blot analysis and by Caspase-Glotrade mark assay. Our findings demonstrate that the use of the Caspase-Glotrade mark assay allows a simple, fast, and sensitive alternative for the evaluation of in vitro response to chemotherapy.