Mazumder D N Guha
DNGM Research Foundation, Kolkata, India.
Indian Pediatr. 2007 Dec;44(12):925-7.
Chronic arsenic toxicity due to drinking of arsenic contaminated water is a major environmental health hazard throughout the world including India. Though lot of information is available on health effects due to chronic arsenic toxicity in adults, knowledge of such effect on children is scanty. A review of available literature has been made to highlight the problem in children.
Scientific publication in journals, monograph, thesis and proceedings of conferences on arsenic in regard to epidemiological, clinical and psychometric studies were reviewed.
Skin abnormalities including pigmentation change and keratosis are the diagnostic signs of chronic arsenic toxicity in adults. Incidence of skin manifestations vary between 1.9-37.1% in various arsenic exposed children populations in different regions of the world. Occurrence of chronic lung disease including pulmonary interstitial fibrosis was described in arsenic exposed children in Chile. Affection of intellectual function is also reported from Thailand, Bangladesh and India.
Chronic arsenic toxicity due to drinking of arsenic contaminated water causes significant morbidity in children in different parts of the world.
饮用受砷污染的水导致的慢性砷中毒是包括印度在内的全世界主要的环境健康危害。虽然有大量关于成人慢性砷中毒对健康影响的信息,但关于其对儿童影响的知识却很匮乏。现对现有文献进行综述以突出儿童中的这一问题。
对期刊、专著、论文以及关于砷的会议论文集中有关流行病学、临床和心理测量学研究的科学出版物进行了综述。
皮肤异常包括色素沉着改变和角化病是成人慢性砷中毒的诊断体征。在世界不同地区的各种砷暴露儿童群体中,皮肤表现的发生率在1.9%至37.1%之间。智利有报道称砷暴露儿童出现包括肺间质纤维化在内的慢性肺病。泰国、孟加拉国和印度也报告了智力功能受到影响。
饮用受砷污染的水导致的慢性砷中毒在世界不同地区的儿童中造成了严重发病情况。