艾菊提取物对乙醇中毒大鼠的肝保护作用。
Hepatoprotector effect of Chrysanthemum balsamita extract in ethanol intoxicated rats.
作者信息
Coprean D, Giurgea R, Rusu M, Tamaş M
机构信息
Biological Research Institute, Cluj-Napoca, Romania.
出版信息
Rev Roum Physiol (1990). 1991 Jan-Jun;28(1-2):27-9.
Male Wistar rats weighing 200 +/- 10 g were intoxicated with ethanol 50% (1 ml/100 g b.w./, day, for 12 days) and concomitantly treated with hydroethanol extract of Chrysanthemum balsamita. An increase of liver glucose-6-phosphatase and phosphorylase a activities correlated with a liver glycogen breakdown as well as a decrease of glycemia were obtained in rats given ethanol 50%. It was found that Chrysanthemum balsamita extract counteracted ethanol effects and maintained at normal limit the metabolite parameters.
体重为200±10克的雄性Wistar大鼠用50%乙醇（1毫升/100克体重/天，持续12天）进行灌胃，并同时用香脂菊水乙醇提取物进行处理。给予50%乙醇的大鼠肝脏葡萄糖-6-磷酸酶和磷酸化酶a活性增加，这与肝糖原分解以及血糖降低相关。结果发现，香脂菊提取物可抵消乙醇的作用，并使代谢参数维持在正常范围内。
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