Dinu V, Zamfir O
Department of Biochemistry, Institute of Medicine and Pharmacy, Bucharest, Romania.
Rev Roum Physiol (1990). 1991 Jan-Jun;28(1-2):69-73.
The present work evaluates some aspects of the redox potential in individuals with insulin-dependent diabetes mellitus (IDDM). The plasma lipid peroxides level and the concentration of glutathione (GSH) were measured. The data obtained revealed a rise in lipoperoxides concentration and a decrease in GSH content suggesting that oxygen derived free radicals may play a role in the pathogenesis of IDDM.
本研究评估了胰岛素依赖型糖尿病（IDDM）患者氧化还原电位的某些方面。测量了血浆脂质过氧化物水平和谷胱甘肽（GSH）浓度。获得的数据显示脂质过氧化物浓度升高，GSH含量降低，这表明氧衍生的自由基可能在IDDM的发病机制中起作用。
