Sukhanova L Ia, Kulikova L A, Galenok V A
Probl Endokrinol (Mosk). 1988 Mar-Apr;34(2):16-7.
The activity of free radical oxidation in patients with diabetes mellitus was investigated with respect to a type of diabetes using chemiluminescence. Clinical, laboratory and instrumental investigation of 80 patients with diabetes mellitus was conducted. The level of free radical oxidation in the patients changed as compared to that in the controls. Direct correlation between an increase in a degree of severity of disease and a rise of the level of chemiluminescence was discovered. Changes of lipid peroxidation in patients with diabetes mellitus permitted sound recommendation of drugs with antioxidant and membrane-stabilizing properties.
利用化学发光法,针对糖尿病类型,对糖尿病患者体内自由基氧化活性进行了研究。对80例糖尿病患者进行了临床、实验室及仪器检查。与对照组相比,患者体内自由基氧化水平发生了变化。发现疾病严重程度的增加与化学发光水平的升高之间存在直接相关性。糖尿病患者脂质过氧化的变化为合理推荐具有抗氧化和膜稳定特性的药物提供了依据。