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大鼠和犬体内（14C）溴苯磷的排泄动力学

Dynamics of excretion (14C) bromfenvinphos in rats and dogs.

作者信息

Ochyński J

机构信息

Department of Toxicological Chemistry, Medical Academy, Lublin, Poland.

出版信息

Pol J Occup Med Environ Health. 1991;4(4):359-75.

PMID:1817684
Abstract

The dynamics of excretion of 14C in rat and dog after a single oral administration of 14C-bromfenvinphos was investigated. The level of radioactivity in urine, faeces and expired air in rats and in urine and faeces in dogs and the level of 14C in rat, depending on the dose and on the position of the labeling of the bromfenvinphos molecule (14C-vinyl) and (14C-ethyl), were determined. Also, the decay of 14C in blood and the retention degree of radioactivity in selected rat tissues were examined.

摘要

研究了大鼠和犬单次口服14C-溴芬磷后14C的排泄动力学。测定了大鼠尿液、粪便和呼出气体以及犬尿液和粪便中的放射性水平，以及取决于剂量和溴芬磷分子标记位置（14C-乙烯基）和（14C-乙基）的大鼠体内14C水平。此外，还检测了血液中14C的衰减情况以及选定大鼠组织中放射性的保留程度。

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