Lin Jiann-Her, Tsai Dong-Han, Chiang Yung-Hsiao
Department of Neurosurgery, Tri-Service General Hospital, 325, Sec. 2, Cheng-Kung Road, Neihu, Taipei 114, Taiwan, ROC.
Pituitary. 2009;12(1):70-5. doi: 10.1007/s11102-007-0081-3.
The development of an esthesioneuroblastoma outside to the region in which olfactory epithelium exists is extremely rare. Only nine cases were reported in the previous literatures. The author presents a 40 years-old man with ectopic esthesioneuroblastoma in sella turcica. In contrast to the previous nine cases, our case presented unusual presentations-CSF rhinorrhea and meningitis. Endoscopic transphenoid approach with removal of tumor and repair of dura defect followed by radiotherapy offered a good result in this case. Moreover, differential diagnosis and the origin of the ectopic esthsioneuroblastoma would be discussed.
嗅神经母细胞瘤发生于嗅上皮所在区域以外的情况极为罕见。既往文献仅报道过9例。作者报告了1例40岁男性，其蝶鞍区存在异位嗅神经母细胞瘤。与既往9例不同，本例表现出不寻常的症状——脑脊液鼻漏和脑膜炎。经鼻内镜蝶窦入路切除肿瘤并修复硬脑膜缺损，随后进行放射治疗，该病例取得了良好效果。此外，还将讨论异位嗅神经母细胞瘤的鉴别诊断及起源。
