Dencker Magnus, Thorsson Ola, Karlsson Magnus K, Lindén Christian, Eiberg Stig, Wollmer Per, Andersen Lars Bo, Ahrén Bo
Department of Clinical Sciences, Malmö, Lund University, Sweden.
Clin Physiol Funct Imaging. 2008 Jul;28(4):211-5. doi: 10.1111/j.1475-097X.2007.00787.x. Epub 2008 Jul 1.
This study explored the associations between body fat versus daily physical activity and insulin concentrations in non-diabetic young children in a cross-sectional study of 172 children (93 boys and 79 girls) aged 8-11 years. Blood samples were analysed for serum insulin and daily physical activity was measured by accelerometers. Time spent performing vigorous activity was estimated from accelerometer data by using established cut-off points. Dual-energy x-ray absorptiometry (DXA) was used to quantify abdominal fat mass (AFM) and total body fat (TBF), also calculated as percentage of body weight (BF%). Body fat distribution was calculated as AFM/TBF. Body fat distribution was independently linked to both insulin concentrations and physical activity. In contrast, TBF, AFM, and BF% were linked to physical activity only and not to insulin concentrations. In conclusion in this population of non-diabetic children, body fat distribution was independently associated with increased concentrations of insulin and deceased amount of vigorous activity per day. Also, AFM, TBF, and BF% were independently related to minutes of vigorous activity per day.
在一项针对172名8至11岁儿童(93名男孩和79名女孩)的横断面研究中,本研究探讨了非糖尿病幼儿体内脂肪与日常身体活动及胰岛素浓度之间的关联。采集血样分析血清胰岛素,并通过加速度计测量日常身体活动。利用既定的临界值,根据加速度计数据估算进行剧烈活动的时间。采用双能X线吸收法(DXA)对腹部脂肪量(AFM)和全身脂肪(TBF)进行量化,也计算为体重百分比(BF%)。身体脂肪分布计算为AFM/TBF。身体脂肪分布与胰岛素浓度和身体活动均独立相关。相比之下,TBF、AFM和BF%仅与身体活动相关,与胰岛素浓度无关。总之,在这群非糖尿病儿童中,身体脂肪分布与胰岛素浓度升高及每日剧烈活动量减少独立相关。此外,AFM、TBF和BF%与每日剧烈活动分钟数独立相关。