Port R V, Arnold J, Kerr D, Glavish N, Winship I
Northern Regional Genetic Service, Auckland District Health Board, Auckland, New Zealand.
Clin Genet. 2008 Feb;73(2):132-8. doi: 10.1111/j.1399-0004.2007.00943.x. Epub 2007 Dec 29.
The delivery of good health care services within clinical settings is predicated by an understanding of the needs of the stakeholders. Most of the information generated to date on the transfer of mutational analysis to clinical service has been within a Eurocentric model favouring individual autonomy. It is predictable that this model does not easily translate for other cultures. Current genetic technology has elucidated the molecular basis of many diseases. In familial cancer and other late-onset disorders, there is now the possibility of 'prediction' where a high risk conferred by family history can be confirmed or negated by genetic testing. In paediatric disorders, prediction is offered in the form of prenatal or pre-implantation genetic diagnosis. We report on the processes undertaken in an attempt to provide a culturally sensitive service for the Maori people of Aotearoa, New Zealand.
在临床环境中提供优质医疗服务的前提是了解利益相关者的需求。迄今为止,关于将突变分析转移到临床服务的大多数信息都是基于以欧洲为中心、支持个人自主权的模式。可以预见,这种模式不容易适用于其他文化。当前的基因技术已经阐明了许多疾病的分子基础。在家族性癌症和其他迟发性疾病中,现在有可能进行“预测”,即通过基因检测来确认或否定家族史所带来的高风险。在儿科疾病中,预测是以产前或植入前基因诊断的形式提供的。我们报告了为新西兰奥特亚罗瓦的毛利人提供具有文化敏感性服务所采取的过程。