Tricco Andrea C, Pham Ba', Rawson Nigel S B
Chalmers Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada.
J Clin Epidemiol. 2008 Feb;61(2):192-197. doi: 10.1016/j.jclinepi.2007.03.009. Epub 2007 Aug 3.
To evaluate the use of two Canadian provincial databases by a systematic review of published studies that used them as a primary data source to answer epidemiologic and health services research questions.
PubMed, EMBASE, BIOSIS, and CINAHL (keywords: "Manitoba" 1970-2004 and "Saskatchewan" 1969-2004) and the web sites of the provincial data custodians were searched to address our objective. Broad screening of citations and data abstraction were performed using a predefined collection form. Information on study characteristics, therapeutic areas studied, databases used, authors' affiliation, and issues related to data validity was recorded.
Three thousand nine hundred and forty-nine citations were screened, 610 studies retrieved, and 325 included. In Saskatchewan, the principal research type was assessment of exposures and health outcomes (48.2%) with 50.4% using a cohort or case-control design, whereas, in Manitoba, it was health services utilization (47.8%) and 86.6% were descriptive. Local investigators performed 83.3% of the Manitoba studies, compared with 35.5% of the Saskatchewan studies. Only 6.2% of the studies assessed the validity and reliability of the database for research purposes and few incorporated relevant information about the validity of their diagnostic data.
Important differences exist in the administration and use of these databases. Similar systematic evidence synthesis should be conducted on other databases.
通过对已发表研究进行系统评价，评估两个加拿大省级数据库的使用情况，这些研究将其作为主要数据源来回答流行病学和卫生服务研究问题。
检索了PubMed、EMBASE、BIOSIS和CINAHL（关键词：“马尼托巴省”1970 - 2004年以及“萨斯喀彻温省”1969 - 2004年）以及省级数据保管机构的网站以实现我们的目标。使用预定义的收集表格对文献进行广泛筛选和数据提取。记录了有关研究特征、所研究的治疗领域、使用的数据库、作者所属机构以及与数据有效性相关问题的信息。
筛选了3949条文献，检索到610项研究，纳入325项。在萨斯喀彻温省，主要研究类型是暴露与健康结局评估（48.2%），50.4%采用队列或病例对照设计；而在马尼托巴省，主要研究类型是卫生服务利用（47.8%），86.6%为描述性研究。马尼托巴省83.3%的研究由当地研究人员开展，相比之下，萨斯喀彻温省这一比例为35.5%。只有6.2%的研究评估了数据库用于研究目的的有效性和可靠性，很少有研究纳入关于其诊断数据有效性的相关信息。
这些数据库在管理和使用方面存在重要差异。应对其他数据库进行类似的系统证据综合分析。
