Débat Zoguéreh D, Bigel M-L, Billy C, Perronne V, Richardin F, Granier F
Service de médecine interne, maladies infectieuses et tropicales, hôpital François-Quesnay, 2, boulevard Sully, 78200 Mantes-la-Jolie, France.
Med Mal Infect. 2008 Apr;38(4):228-30. doi: 10.1016/j.medmal.2007.10.009. Epub 2008 Jan 4.
We report a case of disseminated histoplasmosis due to Histoplasma capsulatum var. capsulatum in an African patient with AIDS (born in Ghana) and living in France. This opportunistic fungal infection has never been reported in Ghana, maybe because of limited means of investigation or ignorance. Nevertheless, it was reported in a Ghanaian immigrant living in Italy. In our patient, the first diagnosis was suggested by a peripheral blood smear, which is not a classical biological diagnostic method. The diagnostic interest and the frequency of positive peripheral blood smears in the course of disseminated histoplasmosis are probably under estimated.
我们报告了一例由荚膜组织胞浆菌荚膜变种引起的播散性组织胞浆菌病病例,患者为一名非洲裔艾滋病患者(出生于加纳),居住在法国。这种机会性真菌感染在加纳从未有过报道,可能是由于调查手段有限或认知不足。不过,在一名居住在意大利的加纳移民中曾有过相关报道。在我们的患者中,首次诊断是通过外周血涂片提出的,这并非经典的生物学诊断方法。外周血涂片在播散性组织胞浆菌病病程中的诊断价值及阳性频率可能被低估了。