Belghiti J, Perniceni T, Kabbej M, Fekete F
Service de Chirurgie digestive, hôpital Beaujon, Clichy.
Chirurgie. 1991;117(5-6):343-6.
Injection of scolicidal solution into the hydatid cysts has been used to sterilize the cyst and to prevent intra-abdominal dissemination of the parasite during surgery. We report six cases of complications of this measure. Intraoperative collapse in one patient and an immediate postoperative death occurring after injection of 10% H202. Postoperative sclerosing cholangitis occurred in 4 patients in whom 2% formalin or 20% sodium chloride was injected into the cyst. Cholangiography showed strictures affecting the intrahepatic biliary tree in 2 and both the intra and extra biliary tree in 3. Sclerosing cholangitis in these patients was likely to result from the caustic effect of the scolicidal solution having diffused from the cyst into the biliary tree. Jaundice developed in 3 patients from 2 to 5 months after operation. The intra-operative collapses is related to the injection of H202 into the cyst. The dramatic increasing of the volume of the cyst may fissure of the cyst-wall and allows the passage of gaz into the circulation. As the efficacity of intracystic injection of a scolicidal solution in preventing the dissemination of the parasite is still unproven, we recommend the rejection of this maneuver in the surgical treatment of hydatid disease of the liver.
向包虫囊肿内注射杀头节液已被用于使囊肿失活,并在手术期间防止寄生虫在腹腔内播散。我们报告了该措施的6例并发症。1例患者在术中注入10%过氧化氢后出现虚脱,1例患者术后立即死亡。4例患者在向囊肿内注入2%福尔马林或20%氯化钠后发生术后硬化性胆管炎。胆管造影显示,2例患者肝内胆管树受累,3例患者肝内外胆管树均受累。这些患者的硬化性胆管炎可能是由于杀头节液的腐蚀性作用从囊肿扩散到胆管树所致。3例患者在术后2至5个月出现黄疸。术中虚脱与向囊肿内注入过氧化氢有关。囊肿体积的急剧增加可能导致囊肿壁破裂,使气体进入循环。由于囊内注射杀头节液在预防寄生虫播散方面的有效性尚未得到证实,我们建议在肝包虫病的手术治疗中摒弃这种操作。