Dufour B, Chrétien Y, Housset M, Baillet F
Hôpital Necker, Service de Chirurgie, Paris.
Chirurgie. 1991;117(5-6):420-2.
The ratio of disappearance of bladder tumors after conventional irradiation (i.e. 45 Gy) is about 30-40%. At least this is the percentage resulting from the study of specimens obtained with total cystectomy, a procedure that remains the usual treatment of these infiltrating cancers. For 30 patients (29 T3 and 1 T2), we have implemented a radio-chemotherapeutic procedure associating 24-Gy radiation to a sensitizing chemotherapy from D1 to D3 and from D15 to D17. Complete response was obtained in 75% of all patients. In one half of the cases in which the response was total, we abstained from removing the bladder, and have noted no signs of recurrence so far.
传统放疗（即45 Gy）后膀胱肿瘤的消失率约为30%-40%。至少这是对全膀胱切除标本研究得出的百分比，全膀胱切除术仍是这些浸润性癌症的常用治疗方法。对于30例患者（29例T3期和1例T2期），我们实施了一种放化疗方案，在第1天至第3天以及第15天至第17天联合24 Gy放疗与增敏化疗。所有患者中有75%获得了完全缓解。在反应完全的病例中，有一半我们没有切除膀胱，目前尚未发现复发迹象。
