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瘙痒性大疱性表皮松解症:一种罕见的常染色体显性变异型。

Epidermolysis bullosa pruriginosa: a rare autosomal dominant variant.

作者信息

Das Sudip, Roy Alok Kumar, Kar Chinmoy, Giri Parag Prasun

机构信息

Department of Skin, STD and Leprosy, Nilratan Sarkar Medical College and Hospital, Kolkata.

出版信息

J Indian Med Assoc. 2007 Jul;105(7):388, 390.

PMID:18178992
Abstract

A 35 years female presented with extremely pruritic, violaceous, small vesiculopapular lesions over both shins since 11/12 years of age. The intensity of pruritus slightly descreased following oozing of fluid. History of similar incidence in her mother and maternal grandfather was present. There was no toe-nail dystrophy. Histopathology report showed the lesions had hyperkeratotic, mild acanthosis, dermal lymphohistiocytic infiltrate and subepidermal cleft. The case was diagnosed to be a case of epidermolysis bullosa pruriginosa.

摘要

一名35岁女性自11或12岁起双小腿出现极度瘙痒的紫蓝色小水疱丘疹性皮损。液体渗出后瘙痒强度稍有减轻。其母亲和外祖父有类似发病史。无趾甲营养不良。组织病理学报告显示皮损有角化过度、轻度棘层肥厚、真皮淋巴细胞组织细胞浸润及表皮下裂隙。该病例被诊断为瘙痒性大疱性表皮松解症。

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