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新生马耳他幼驹出生后第一周的凝血指标

Clotting profiles in newborn maltese kids during the first week of life.

作者信息

Piccione Giuseppe, Bertolucci Cristiano, Giannetto Claudia, Giudice Elisabetta

机构信息

Dipartimento di Morfologia, Biochimica, Fisiologia e Produzione Animale, Facoltà di Medicina Veterinaria, Università di Messina, Messina, Italy 98168.

出版信息

J Vet Diagn Invest. 2008 Jan;20(1):114-8. doi: 10.1177/104063870802000126.

Abstract

The neonatal period is probably the only time when a higher incidence of spontaneous thromboembolic complications may occur in the otherwise normal, healthy individual. This study was designed to determine the postnatal development of the kid coagulation system. Ten clinically healthy and full-term-born Maltese kid goats (5 males and 5 females) were used. In each kid, during the first week after birth, the prothrombin time (PT), the activated partial thromboplastin time (aPTT), the thrombin time (TT), and fibrinogen were assessed. Analysis of variance showed a highly significant effect of age on PT, TT, and fibrinogen. Our results of this study indicate that the clotting mechanism in kids is influenced by growth. This investigation contributes to the knowledge of clotting adaptations in kids during the first 7 days of life and provides useful information for the diagnosis and treatment of some neonatal diseases.

摘要

新生儿期可能是唯一在其他方面正常、健康的个体中自发血栓栓塞并发症发生率较高的时期。本研究旨在确定幼畜凝血系统的产后发育情况。使用了10只临床健康、足月出生的马耳他幼山羊(5只雄性和5只雌性)。在每只幼畜出生后的第一周内,对凝血酶原时间(PT)、活化部分凝血活酶时间(aPTT)、凝血酶时间(TT)和纤维蛋白原进行了评估。方差分析显示年龄对PT、TT和纤维蛋白原有高度显著影响。我们这项研究的结果表明,幼畜的凝血机制受生长影响。本研究有助于了解幼畜出生后7天内的凝血适应性,并为某些新生儿疾病的诊断和治疗提供有用信息。

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