健康成年家养山羊（Capra aegagrus hircus）凝血变量的参考区间。
Reference intervals for coagulation variables in healthy adult domestic goats (Capra aegagrus hircus).
作者信息
Zersen Kristin M, Russell Moore A, Olver Christine S, Mathis Justin C
机构信息
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
出版信息
Vet Clin Pathol. 2018 Sep;47(3):396-399. doi: 10.1111/vcp.12621. Epub 2018 Jul 9.
BACKGROUND
Coagulation has not been studied extensively in adult goats, and reference intervals (RIs) for coagulation variables have not yet been established and would be clinically useful.
OBJECTIVES
The goal of this study was to establish coagulation variable RIs in adult goats for future coagulation interpretation.
METHODS
Blood samples from 40 healthy adult goats were collected, and assays for PT, APTT, D-dimers, antithrombin III, and fibrinogen were performed. Coagulation variable RIs were established using the Reference Value Advisor v2.1.
RESULTS
The RIs included: PT, 15.7-19.8 seconds; APTT, 16.2-24.3 seconds; D-dimer, 0-0.68 μg/mL; antithrombin III, 108.6%-156.5%; fibrinogen, 89.5-303.2 mg/dL.
CONCLUSIONS
In this brief communication, we report the RIs for coagulation variables in healthy adult goats. Further research will be needed to identify coagulation changes that are associated with specific disease processes of goats.
背景
成年山羊的凝血情况尚未得到广泛研究，凝血变量的参考区间（RIs）尚未确立，但在临床上会很有用。
目的
本研究的目的是确立成年山羊的凝血变量参考区间，以便未来进行凝血解读。
方法
采集40只健康成年山羊的血样，进行凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、D-二聚体、抗凝血酶III和纤维蛋白原检测。使用参考值顾问v2.1确立凝血变量参考区间。
结果
参考区间包括：PT，15.7 - 19.8秒；APTT，16.2 - 24.3秒；D-二聚体，0 - 0.68μg/mL；抗凝血酶III，108.6% - 156.5%；纤维蛋白原，89.5 - 303.2mg/dL。
结论
在本简短通讯中，我们报告了健康成年山羊凝血变量的参考区间。需要进一步研究以确定与山羊特定疾病过程相关的凝血变化。
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