Thirion Laurence, Nikkels Arjen F, Piérard Gérald E
Department of Dermatopathology, University Medical Center of Liège, Liège, Belgium.
Dermatology. 2008;216(3):227-8. doi: 10.1159/000112930. Epub 2008 Jan 9.
Etoricoxib is a new, highly selective cyclooxygenase (COX) 2 inhibitor, reported to have an increased cutaneous and systemic safety profile compared to the previous COX-2 inhibitors, including celecoxib, rofecoxib and valdecoxib. To the best of our knowledge, the present case of etoricoxib-induced erythema-multiforme-like eruption is the first reported in the literature.
依托考昔是一种新型的、高选择性的环氧化酶(COX)2抑制剂,据报道,与包括塞来昔布、罗非昔布和伐地昔布在内的先前COX-2抑制剂相比,其皮肤和全身安全性更高。据我们所知,本病例为依托考昔诱发的多形红斑样皮疹,是文献中首次报道。