一种来自多花山椒的新型抗利什曼原虫半日花烷型二萜。
A novel leishmanicidal labdane from Polyalthia macropoda.
作者信息
Richomme P, Godet M C, Foussard F, Toupet L, Sévenet T, Bruneton J
机构信息
C.E.P.M., Faculté de Pharmacie, Angers, France.
出版信息
Planta Med. 1991 Dec;57(6):552-4. doi: 10.1055/s-2006-960204.
PMID:1818347
Abstract
A new diterpene, (4S,9R,10R) methyl 18-carboxy-labda-8,13(E)-diene-15-oate has been obtained from the stem barks of Polyalthia macropoda (Annonaceae). This labdanic derivative was identified on the basis of spectroscopic data and is biologically active against the promastigote Leishmania donovani donovani.
摘要
从多脉暗罗（番荔枝科）的茎皮中获得了一种新的二萜类化合物，即(4S,9R,10R)-18-羧基-喇叭茶-8,13(E)-二烯-15-酸甲酯。该赖百当型衍生物是根据光谱数据鉴定的，并且对杜氏利什曼原虫前鞭毛体具有生物活性。
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