Hammarström Lennart, Weiner Carina Krüger
Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge, SE-141 86, Stockholm, Sweden.
Adv Exp Med Biol. 2008;606:321-43. doi: 10.1007/978-0-387-74087-4_13.
Bovine colostrum contains immunoglobulins that provide the newborn calf with protection against microbial infections until its own immune system matures. The concentration of antibodies in colostrum against pathogens can be raised by immunizing cows with pathogens or their antigens. Bovine colostrum-based immune milk products have proven efficacy in prophylaxis and treatment against various infectious diseases in humans such as diarrheal diseases caused by various pathogens like E. coli and rotavirus. Still, future attempts are needed to increase the yield and the concentration of antibodies in order to achieve full protection.
牛初乳含有免疫球蛋白,在新生小牛自身免疫系统成熟之前,为其提供针对微生物感染的保护。通过用病原体或其抗原免疫母牛,可以提高初乳中针对病原体的抗体浓度。基于牛初乳的免疫奶制品已被证明在预防和治疗人类各种传染病方面有效,如由大肠杆菌和轮状病毒等各种病原体引起的腹泻病。然而,为了实现全面保护,未来仍需要努力提高抗体产量和浓度。