Sprangers B, Smets S, Sagaert X, Wozniak A, Wollants E, Van Ranst M, Debiec-Rychter M, Sciot R, Vanrenterghem Y, Kuypers D R
Department of Nephrology, University Hospital Gasthuisberg, Leuven, Belgium.
Am J Transplant. 2008 Jan;8(1):253-8. doi: 10.1111/j.1600-6143.2007.02054.x.
Epstein-Barr virus (EBV) has been implicated in the pathogenesis of different types of malignancies. While nonmelanoma skin cancers, lymphomas and Kaposi sarcomas are the most frequently reported malignancies after solid organ transplantation, EBV-associated smooth muscle tumors (EBV-SMT) after transplantation are rare and thus far only 18 cases in kidney recipients have been reported. A case of a 51-year-old kidney transplant recipient diagnosed with EBV-SMT is reported together with a review of the literature.
爱泼斯坦-巴尔病毒(EBV)与不同类型恶性肿瘤的发病机制有关。虽然非黑色素瘤皮肤癌、淋巴瘤和卡波西肉瘤是实体器官移植后最常报告的恶性肿瘤,但移植后与EBV相关的平滑肌瘤(EBV-SMT)却很罕见,迄今为止,仅报告了18例肾移植受者病例。本文报告了一例51岁肾移植受者诊断为EBV-SMT的病例,并对相关文献进行了综述。